Biofilm simulation series: QS+ and EPS+ cells

Nadell et al. 2008D Nadell, Carey; B Xavier, João; A Levin, Simon; R Foster, Kevin (2008): The Evolution of Quorum Sensing in Bacterial Biofilms. Biology. 10.1371/journal.pbio.0060014.sv001.

If biofilm formation is simulated beginning with a mixed population of quorum sensing  sensitive (QS+) and extracellular matrix producing (EPS+) cells, as autoducer levels rise (shown as blue gradations from below) above a critical threshold, QS+ cells stop producing matrix and shift their metabolism towards biomass production.  This leads to bursts of growth in cells exposed to maximum nutrient levels at the top of tower structures during the later stages of biofilm development.

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